ODCs

Cytoscape Web

Click node...

Hereditary vascular retinopathy

1 OMIM reference -
1 associated gene
3 signs/symptoms

PROTEIN INTERACTIONS: 1
COMMON SIGNS: 1

Muir-Torre syndrome

1 OMIM reference -
3 associated genes
14 signs/symptoms

Hereditary vascular retinopathy

Muir-Torre syndrome

TREX1	(UniProt - OMIM)		MLH1	(UniProt - OMIM)
			MSH2	(UniProt - OMIM)
			MSH6	(UniProt - OMIM)


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	TREX1	(0.62)	MSH2

Citations in the biomedical literature:

Hereditary vascular retinopathy		Muir-Torre syndrome
	Synonym(s): - HVR - Hereditary vascular retinopathy - Raynaud phenomenon - migraine		Synonym(s): - Multiple keratoacanthoma, Muir-Torre type

	Classification (Orphanet): - Rare eye disease - Rare genetic disease - Rare neurologic disease		Classification (Orphanet): - Rare eye disease - Rare gastroenterologic disease - Rare genetic disease - Rare oncologic disease - Rare skin disease

	Classification (ICD10): (no data available)		Classification (ICD10): - Neoplasms -

	Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: adulthood Average age of death: no data available Type of inheritance: autosomal dominant		Epidemiological data: Class of prevalence: unknown Average age onset: adulthood Average age of death: - Type of inheritance: autosomal dominant

	External references: 1 OMIM reference - No MeSH references		External references: 1 OMIM reference - 1 MeSH reference: D055653


COMMON SIGNS	- Autosomal dominant inheritance

Hereditary vascular retinopathy		Muir-Torre syndrome
	Very frequent - Anomalies of eyes and vision - Visual loss / blindness / amblyopia		Very frequent - Adenoma sebaceum - Skin tumors / lumps / epidermal cysts Frequent - Colon neoplasm / tumor / carcinoma / cancer - Estomach / gastric neoplasm / tumor / carcinoma / cancer Occasional - Breast neoplasm / tumor / carcinoma / cancer - Hematologic / blood / lymphatic cancer - Hepatic / liver neoplasm / tumor / carcinoma / cancer - Kidney / renal neoplasm / tumor / carcinoma / cancer - Laryngeal neoplasm / tumor / carcinoma / cancer - Ovary / Fallopian tube neoplasm / tumor / carcinoma / cancer (excl. teratoma / germinoma) - Salivary gland neoplasm / tumor / carcinoma / cancer - Ureteral / urethral / vesical / bladder neoplasm / tumor / carcinoma / cancer - Uterus / uterine / cervix / endometrium neoplasm / tumor / carcinoma / cancer